AbstractRoss River fever (RRF), caused by Ross River virus (RRV), represents Australia's most significantmosquito-borne disease, with approximately 5,000 cases reported annually. This publicationexamines the ecological homeostatic mechanisms that regulate RRV transmission dynamicsacross diverse Australian ecosystems. Through analysis of vector-host-environment interactions,we identify key regulatory processes that maintain epidemic potential within bounded parameterswhile responding to climatic and anthropogenic perturbations. The transmission cycle demonstratescomplex homeostatic regulation involving over 40 mosquito vector species, multiple marsupialreservoir hosts, and diverse wetland habitats. Climate change and urbanization are disrupting thesehomeostatic equilibria, leading to unprecedented outbreak patterns and geographical expansion.Understanding these ecological regulatory mechanisms provides critical insights for predictivemodeling, surveillance optimization, and integrated management strategies. This analysiscontributes to the theoretical framework of ecological homeostasis in vector-borne disease systemsand offers practical applications for Australian public health policy.Keywords: Ross River virus, ecological homeostasis, vector-borne disease, mosquito ecology,Australia, climate change, epidemic dynamics, wetland ecosystems
Smith et al. (Thu,) studied this question.