The reviewed studies showed that fractal dimension and texture parameters were useful for evaluating lesions and distinguishing normal and pathological tissues; however, there is a lack of methodological standardization. Although fractal dimension was assessed in all articles, lacunarity was examined in just one. Binarization and segmentation impact fractal dimension, lacunarity, and other texture measurements, which can be significantly enhanced by appropriate image processing. In contrast, poorly executed preprocessing may lead to misinterpretation of results.
Poletto et al. (Thu,) studied this question.