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An organ-conformal, kirigami-structured bioelectronic patch for precise intracellular delivery | Synapse
March 3, 2026
An organ-conformal, kirigami-structured bioelectronic patch for precise intracellular delivery
YW
Yuqiong Wang
City University of Hong Kong
LD
Lamei Du
Hebei University of Technology
HW
Han Wu
Wenzhou University
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Key Points
Enhanced intracellular delivery is achieved using a kirigami-structured bioelectronic patch, which conforms to the organ's shape.
The bioelectronic patch shows a significant improvement in targeting precision compared to conventional methods.
Assessment involved evaluating tissue conformability and delivery efficiency using in vivo models for validation.
The innovative design highlights potential therapeutic applications, although further testing in human models is necessary.
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Wang et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75a57c6e9836116a200da
https://doi.org/https://doi.org/10.1016/j.cell.2025.12.021