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Repurposing FDA-approved drugs as multi-stage antimalarials: An in silico investigation | Synapse
March 3, 2026
Open Access
Repurposing FDA-approved drugs as multi-stage antimalarials: An in silico investigation
AD
Afolayan Funmilayo I D
AA
Adewoyin H. Ademola
SA
Salaam Ridwan A
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Key Points
Findings reveal several FDA-approved drugs with potential as multi-stage antimalarials, enhancing treatment options.
The investigation utilized in silico techniques, including molecular docking, for drug repurposing analysis.
Assessment involved targeting multiple stages of the malaria parasite lifecycle, crucial for effective treatment.
These results highlight the promise of existing medications in tackling malaria, but clinical trials are necessary.
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D et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75acec6e9836116a211b5
https://doi.org/https://doi.org/10.1016/j.insi.2026.100209