Preparation and antimicrobial activity of Mono-, Bis, and Tris-4,9-Dihydroxy-7,7-Dimethyl-5-(mono-substituted-aryl)-Hexahydro-Indeno1,2-bIndole-9,10-Dione derivatives

Key Points

• Antimicrobial activity shows promise against various bacterial strains, particularly with specific substitutions.
• The study highlights 4,9-dihydroxy-7,7-dimethyl-5-mono-substituted-aryl compounds as effective agents.
• Chemical synthesis involving mono-, bis-, and tris-substituted derivatives revealed varied efficacy in the bioactivity assay.
• These findings support the exploration of indole derivatives in developing new antimicrobial agents.