KRTCAP2 accelerates malignant progression through modulating tumor cell function and M2 macrophage infiltration in glioma

Key Points

• KRTCAP2 serves as a novel prognostic biomarker, affecting tumor cell function and macrophage infiltration in glioma microenvironments.
• Findings show that KRTCAP2 modulates the immunosuppressive environment, influencing tumor progression and treatment response.
• Observational analysis across clinical cases highlights the significant role of KRTCAP2 in immune modulation within glioma.
• These results indicate that KRTCAP2 could be a promising therapeutic target, pointing to the need for further investigations.