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March 3, 2026
Open Access
Astrocyte CB1 receptors drive blood-brain barrier disruption in central nervous system inflammatory disease
TC
Teresa Colomer
AB
Ana Bernal-Chico
ES
Ester Sánchez-Martín
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Key Points
Disruption of the blood-brain barrier is linked to astrocyte cb1 receptors in inflammatory diseases.
The study highlights the significance of astrocytes in maintaining central nervous system integrity during inflammation.
Findings indicate that targeting cb1 receptors may offer new therapeutic avenues in treating CNS inflammatory conditions.
Further research is needed to explore the precise mechanisms of cb1 receptor involvement in blood-brain barrier disruption.
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Colomer et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75bb0c6e9836116a23798
https://doi.org/https://doi.org/10.1186/s12974-026-03708-3
Astrocyte CB1 receptors drive blood-brain barrier disruption in central nervous system inflammatory disease | Synapse