Clinical significance of corneal confocal microscopy characteristics and inflammatory cytokines in Sjgren's syndrome-related dry eye disease

Key Points

• DCD levels are the most predictive factor for dry eye disease in Sjögren's syndrome.
• Elevated IL-1β, OSDI, DCD, and ICD are identified as independent risk factors for the condition.
• Assessment utilized corneal confocal microscopy to evaluate the inflammatory cytokines and their impact on dry eye disease.
• Findings indicate DCD may serve as a reliable biomarker for diagnosis and ongoing disease monitoring.