Preserved Contrast Sensitivity in Early and Intermediate Age-Related Macular Degeneration and Marked Loss in Late Stage: ALSTAR2 | Synapse
March 3, 2026Open Access
Preserved Contrast Sensitivity in Early and Intermediate Age-Related Macular Degeneration and Marked Loss in Late Stage: ALSTAR2
Key Points
Contrast sensitivity remains intact in early and intermediate age-related macular degeneration (AMD).
Loss becomes notable in late-stage AMD, indicating a critical transition point.
Assessment utilized qCSF, emphasizing its utility for understanding AMD progression.
Understanding these phases may improve clinical strategies and patient outcomes in AMD.
Abstract
The qCSF will be most useful in trials studying the transition from intermediate AMD to late-stage AMD, rather than in studying the transition from aging to early and intermediate AMD.