Sperm DNA fragmentation and its influence on mammalian reproduction

Key Points

• Sperm DNA fragmentation significantly impacts fertility outcomes, leading to reduced reproductive performance in mammals.
• Infertility is observed in mammals with high levels of sperm DNA fragmentation, impacting chromatin integrity.
• Analysis of various reproductive studies highlights the correlation between sperm DNA quality and successful fertilization rates.
• High sperm DNA fragmentation levels may prompt the need for advanced fertility treatments and strategic reproductive planning.