March 3, 2026Open Access

Expression profile of circular RNAs in type 2 diabetes mellitus patients with retinopathy

Key Points

Downregulated circRNAs were identified, particularly hsa_circRNA_407262, which may indicate a pivotal role in the development of diabetic retinopathy.
Three specific circRNAs were found to be upregulated, shedding light on the potential molecular pathways involved.
The assessment involves a comprehensive profiling of circRNAs in type 2 diabetes patients with diabetic retinopathy.
Findings may prompt further investigation into circRNAs as viable biomarkers for early diagnosis of diabetic retinopathy.

Abstract

This study identified five downregulated and three upregulated circRNAs associated with DR. Among them, hsacircRNA₄07262 may play a crucial role in the pathological process of DR and holds potential as a candidate biomarker for early diagnosis.

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Discussion

Authors

Wencheng An

Beijing Haidian Hospital

Bingyan Wang

Peking University

Fang Chen

Beijing Haidian Hospital

Journals

Journal of Diabetes Investigation

Actions

Institutions

Peking University

Peking University Third Hospital

Beijing Haidian Hospital

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Expression profile of circular RNAs in type 2 diabetes mellitus patients with retinopathy

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

Cite this study

Also consider

Also consider