Synthesis, in vitro antimicrobial evaluation and computational insights into new bipyridinyl-coumarin hybrids

Key Points

• New bipyridinyl-coumarin hybrids demonstrate notable antimicrobial effects against tested organisms.
• The synthesized compounds showed effectiveness with notable improvements in activity rates compared to traditional agents.
• Assessment using in vitro testing and computational insights provides a comprehensive evaluation of these hybrids.
• The findings indicate that these novel hybrids could lead to more effective antimicrobial strategies.