March 3, 2026Open Access

AFI ‐Guided Detection and Biopsy of Pulmonary MALT Lymphoma With Bilateral Endobronchial Involvement

Key Points

Complete metabolic response observed after rituximab treatment shows the effectiveness of this approach.
AFI bronchoscopy identified bilateral endobronchial lesions leading to a confirmed diagnosis of MALT lymphoma.
Patient presenting with blood-stained sputum underwent PET CT revealing a right upper lobe lesion without nodal disease.
The case highlights the importance of utilizing advanced imaging techniques for early diagnosis of pulmonary conditions.

Abstract

A 74-year-old man with prior stage IE gastric MALT lymphoma presented with blood-stained sputum. Autofluorescence imaging (AFI) bronchoscopy revealed bilateral endobronchial lesions; with biopsies confirmed MALT lymphoma. Positron emission tomography computed tomography showed right upper lobe lesion without nodal disease. He received rituximab, with complete metabolic response. AFI facilitated early airway-focused diagnosis.

AFI ‐Guided Detection and Biopsy of Pulmonary MALT Lymphoma With Bilateral Endobronchial Involvement

Key Points

Abstract

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