Small EVs miRNA profiles and their expressions in EVs-depleted plasma as an optimal combination panel for treatment-resistant schizophrenia

Key Points

• Small EVs miRNA profiles may enhance our understanding of treatment-resistant schizophrenia.
• The study analyzed genetic expression in EVs-depleted plasma, focusing on critical biomarkers.
• Observational analysis of EVs showed significant alterations in miRNA levels in patients with schizophrenia.
• Identifying these biomarkers may improve diagnostic and therapeutic approaches for treatment-resistant cases.