Comparison of the phenolic and antioxidant potential of five European herbal remedies by effect-directed analysis using offline two-dimensional liquid chromatography-high resolution mass spectrometry

Key Points

• Antioxidant potential varies significantly among the five herbal remedies analyzed, indicating diverse efficacy.
• Key findings reveal specific phenolic compounds responsible for high antioxidant activity in these remedies.
• Effect-directed analysis combined with two-dimensional liquid chromatography and mass spectrometry was employed for comprehensive profiling.
• Highlights the need for further exploration of natural antioxidants from herbal sources, which may benefit health.