Quercetin induces ferroptosis in ovarian cancer through regulating HSPB1/Notch1 pathway

Key Points

• Quercetin effectively triggers ferroptosis in ovarian cancer cells, promoting tumor cell death.
• The study showed a significant increase in ferroptosis markers post-treatment with quercetin.
• Analysis of cell viability and signaling pathways highlighted the involvement of HSPB1 and Notch1 in this process.
• This finding supports potential quercetin-based therapies for ovarian cancer; further investigation is warranted.