Primary and metastatic brain tumours in hereditary cancer syndromes: case reports with and literature review | Synapse
March 3, 2026Open Access
Primary and metastatic brain tumours in hereditary cancer syndromes: case reports with and literature review
Key Points
Genetic testing for germline mutations is crucial in primary and metastatic brain tumours, enhancing diagnosis and treatment plans.
Identifying high-risk cancer syndromes can inform monitoring strategies for early detection of brain tumours.
Observational analysis shows a strong link between genetic predispositions and the presence of brain tumours, underscoring the need for genetic counseling.
The study suggests that better understanding of hereditary risks may improve clinical outcomes in affected individuals.
Abstract
In all primary and metastatic brain tumours, genetic testing for germline mutations of high-risk cancers should be considered.