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The metabolic signature of excessive endurance exercise—A prospective study in Tour de France cyclists | Synapse
March 3, 2026
Open Access
The metabolic signature of excessive endurance exercise—A prospective study in Tour de France cyclists
RR
Ruben Robberechts
Hasselt University
MS
Myrthe Stalmans
University of British Columbia
WL
Wout Lauriks
Materialise (Belgium)
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Key Points
Excessive endurance exercise alters the metabolic signature in cyclists, indicating potential health effects.
A notable increase in lactate levels was observed among Tour de France cyclists during the study.
Observational analysis focused on the metabolic responses of cyclists during intensive training regimens.
These findings may highlight risks associated with high levels of endurance exercise, warranting further investigation to assess long-term effects.
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Robberechts et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75d6bc6e9836116a2771c
https://doi.org/https://doi.org/10.1016/j.isci.2026.114838