Chest muscle area, spleen density, CD4 + T%, and C4 to predict the development of interstitial lung disease in patients with Sjögren’s syndrome: a clinical prediction model

Key Points

• Chest muscle area and spleen density correlate significantly with the development of interstitial lung disease.
• Key metrics include CD4+ T cell percentage and C4 levels, which were analyzed statistically.
• The model demonstrated robustness through clinical evaluation in patients diagnosed with Sjögren’s syndrome.
• Findings may enhance early intervention strategies for patients at risk of interstitial lung disease.