A novel strategy based on serum metabolite-mediated interactions between the lung and gut microbiota to investigate the protective effect of Flos Farfarae against chronic bronchitis

Key Points

• Flos Farfarae displayed significant protective effects against chronic bronchitis.
• Serum metabolites were key mediators in the interaction between lung and gut microbiota.
• This study utilized an observational analysis methodology to understand these interactions.
• These findings highlight the potential for novel therapeutic strategies based on microbiota interactions.