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Baitouweng decoction regulates ferroptosis-mediated mitophagy and apoptosis through the SLC7A11/GPX4/FTH1 pathway in ulcerative colitis | Synapse
March 3, 2026
Baitouweng decoction regulates ferroptosis-mediated mitophagy and apoptosis through the SLC7A11/GPX4/FTH1 pathway in ulcerative colitis
LZ
L Zhang
Nanjing University of Chinese Medicine
XZ
Xiaolan Zhu
Nanjing University of Chinese Medicine
XH
Xiaochao Hu
Nanjing University of Chinese Medicine
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Key Points
Ferroptosis and mitophagy are crucial in regulating apoptosis in ulcerative colitis, enhancing treatment strategies.
Baitouweng decoction significantly influences the slc7a11/gpx4/fth1 pathway, potentially guiding new therapies.
This analysis addresses the role of different molecular pathways in ulcerative colitis, offering insights for future research.
Understanding these mechanisms may enable better management of ulcerative colitis and improve patient outcomes.
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Zhang et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75d99c6e9836116a27c5a
https://doi.org/https://doi.org/10.1016/j.phymed.2026.157898