Paeonol inhibits the progression of endometrial cancer by affecting TRIM26-mediated LDHA ubiquitination modification

Key Points

• Inhibition of endometrial cancer progression is noted, with a specific focus on the role of TRIM26 in regulating LDHA.
• Paeonol treatment significantly influences LDHA ubiquitination, which may alter cancer cell behavior increasing treatment prospects.
• Interventions involve the application of paeonol, revealing insights into its mechanisms affecting LDHA and TRIM26 interactions.
• This study highlights novel therapeutic avenues, indicating potential applications for paeonol in treating endometrial cancer.