A Study on the Network Pharmacology of HQGZWWT that Prevents CINP by Inhibiting Ferroptosis through Regulation of the P38/c-FOS/NF-kB Pathway

Key Points

• Inhibition of ferroptosis significantly reduces CINP, suggesting potential treatment avenues.
• The observed effects are mediated through the modulation of the p38/c-FOS/NF-kB pathway, a critical molecular route.
• Analysis of network pharmacology reveals multiple interactions affecting the ferroptosis mechanism.
• The findings highlight the importance of targeted therapies in addressing CINP, yet further validation is necessary.