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Global prevalence and trends of fluconazole resistance in non-albicans Candida species: a systematic review and meta-analysis | Synapse
March 3, 2026
Open Access
Global prevalence and trends of fluconazole resistance in non-albicans Candida species: a systematic review and meta-analysis
XL
Xuehua Li
Shandong University of Technology
MS
Mohammad Sholeh
Pasteur Institute of Iran
MM
Mahya Abedi Moghadam
Golestan University
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Key Points
Fluconazole resistance has increased significantly in non-albicans Candida species.
The review estimates a resistance prevalence of approximately 30% across various regions.
Systematic review and meta-analysis of global data highlight alarming resistance trends.
Addressing this issue is critical for effective treatment strategies and patient outcomes.
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Li et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75dffc6e9836116a2854f
https://doi.org/https://doi.org/10.1186/s12879-026-12653-8