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miRNA-214 to predict progression and survival in ALS | Synapse
March 3, 2026
miRNA-214 to predict progression and survival in ALS
MN
Min‐Young Noh
Hanyang University Seoul Hospital
MK
Min‐Soo Kwon
CHA University
KO
Ki-Wook Oh
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Key Points
miRNA-214 indicates potential progression and survival outcomes in ALS, helping to assess disease severity.
In an observational analysis, increased miRNA-214 levels correlate with poorer survival in ALS patients over two years.
Utilizing biomarkers, the study identifies miRNA-214's critical role in regulatory pathways impacting ALS progression.
Findings highlight the significance of miRNA-214 as a potential therapeutic target for enhancing ALS management.
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Noh et al. (Mon,) studied this question.
synapsesocial.com/papers/69a75ed6c6e9836116a29cb5
https://doi.org/https://doi.org/10.1016/j.jns.2025.124719
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