March 3, 2026Open Access

Low-density asymptomatic parasitemia in southern Zambia does not lead to clinical malaria and is not associated with household transmission: results from a two-year cohort study

Key Points

Low-density asymptomatic parasitemia does not result in cases of clinical malaria.
No evidence suggests that parasitemia contributes to malaria transmission among household members.
Cohort study investigated this phenomenon over two years in southern Zambia.
Findings highlight the need for further research in similar low transmission settings.

Abstract

Low-level parasitemia was prevalent despite few cases of clinical malaria in this low transmission setting. There was no evidence that low-level asymptomatic parasitemia led to clinical cases of malaria or transmission to other household members.

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Authors

Jessica L. Schue

Johns Hopkins University

André‐Guy Martin

Centre hospitalier universitaire de Québec

Japhet Matoba

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Institutions

Johns Hopkins University

University of Florida

Golden Valley Agricultural Research Trust

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Low-density asymptomatic parasitemia in southern Zambia does not lead to clinical malaria and is not associated with household transmission: results from a two-year cohort study

Key Points

Abstract

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Discussion

Authors

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Institutions

References and Citations

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Discussion

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