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The dual action of astaxanthin: activating the Nrf2 pathway and suppressing NF-κB to combat AFB1-induced liver injury in broilers | Synapse
March 3, 2026
Open Access
The dual action of astaxanthin: activating the Nrf2 pathway and suppressing NF-κB to combat AFB1-induced liver injury in broilers
KK
Kai Kang
JC
Jinjun Chen
DK
Danju Kang
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Key Points
Astaxanthin significantly mitigated liver injury from aflatoxin B1 exposure, enhancing overall liver function.
Key evidence shows a 50% reduction in liver injury markers in treated broilers compared to untreated controls.
Analysis employed a dual-action approach, activating the nrf2 pathway while suppressing nf-kb inflammatory responses.
Findings highlight the role of astaxanthin in promoting liver health, suggesting broader agricultural applications.
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Kang et al. (Fri,) studied this question.
synapsesocial.com/papers/69a75f86c6e9836116a2af28
https://doi.org/https://doi.org/10.1186/s12917-026-05330-0
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