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Gut brain axis dysfunction: A potential biomarker for early diagnosis of Parkinson disease | Synapse
March 3, 2026
Gut brain axis dysfunction: A potential biomarker for early diagnosis of Parkinson disease
AM
Ayesha Mansoor
AS
Amna Sanaullah
MI
Muhammad Ibrahim
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Key Points
Dysfunction of the gut brain axis may serve as a biomarker for early diagnosis of Parkinson disease, indicating a new approach to identification.
The study highlights significant correlations between gut microbiota changes and early neurological symptoms in Parkinson disease.
Assessment utilized a comprehensive analysis of gut microbiota composition, emphasizing its relationship with disease onset and progression.
These findings support the idea that early intervention based on gut health could improve outcomes for patients with Parkinson disease.
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Cite This Study
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Mansoor et al. (Mon,) studied this question.
synapsesocial.com/papers/69a75f9ec6e9836116a2b1f3
https://doi.org/https://doi.org/10.1016/j.jns.2025.125286