Mediating role of maternal cortisol in the association between maternal serum creatinine and fetal cortisol exposure

Key Points

• Fetal cortisol exposure significantly associates with maternal serum creatinine levels, indicating potential metabolic links.
• Higher maternal serum creatinine levels correlated with increased fetal cortisol exposure, emphasizing the need for monitoring.
• Analysis of maternal cortisol mediation highlights its role in fetal hormonal exposure pathways and developmental impacts.
• Findings suggest that understanding maternal hormonal regulation may improve fetal health evaluations during pregnancy.