Targeting RIG-I alleviates renal tubular epithelial cells PANoptosis during post-traumatic rhabdomyolysis

Key Points

• Targeting RIG-I alleviates PANoptosis in renal tubular epithelial cells after rhabdomyolysis.
• A significant reduction in cytokines was observed, indicating an improved cellular response.
• The approach used includes assessments of renal tubular epithelial cells' viability post-injury.
• This highlights the potential for RIG-I targeting in managing rhabdomyolysis-related kidney injury.