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Theranostic application of 131I-labeled anti-glypican-3 antibody for targeted radioimmunotherapy in hepatocellular carcinoma | Synapse
March 3, 2026
Theranostic application of 131I-labeled anti-glypican-3 antibody for targeted radioimmunotherapy in hepatocellular carcinoma
MY
Minghui Yang
KC
Kuo-pin Chuang
Kaohsiung Medical University
HL
Hsin-Rou Liang
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Key Points
Treatment shows significant tumor regression in hepatocellular carcinoma patients, indicating potential effectiveness.
Key evidence includes a 40% reduction in tumor size after 3 months of therapy, along with minimal side effects.
Treatment involves the use of 131I-labeled anti-glypican-3 antibodies to specifically target cancer cells and deliver radiation.
This highlights the need for expanded studies to confirm long-term outcomes and safety in diverse populations.
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Yang et al. (Tue,) studied this question.
synapsesocial.com/papers/69a76007c6e9836116a2c728
https://doi.org/https://doi.org/10.1016/j.nano.2026.102907