March 3, 2026Open Access

Reduction of serum bilirubin levels after endoscopic biliary drainage in patients with extrahepatic biliary obstruction and its significance

Key Points

Reduction of serum bilirubin levels by day 7 predicts reintervention likelihood for patients.
Achieving bilirubin levels below 3 mg/dL by day 15 is crucial for short-term survival.
Assessment of bilirubin kinetics following endoscopic biliary drainage provides reliable prognostic indicators.
Identifying bilirubin thresholds can help guide clinical decisions and improve patient outcomes.

Abstract

Failure to achieve ≥ 50% fall by day 7 predicts reintervention, while inability to reach bilirubin < 3 mg/dL by day 15 predicts mortality. Bilirubin kinetics following EBD serve as reliable indicators of drainage adequacy and short-term prognosis in EHBO.

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