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Real World Experience of Anakinra for the Treatment of Immune Effector Cell-Associated Neurotoxicity Syndrome in Large B-cell Lymphoma | Synapse
March 3, 2026
Real World Experience of Anakinra for the Treatment of Immune Effector Cell-Associated Neurotoxicity Syndrome in Large B-cell Lymphoma
RS
Rahul Shah
XS
Xiaowen Sun
The University of Texas MD Anderson Cancer Center
LF
Lei Feng
The University of Texas MD Anderson Cancer Center
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Key Points
Anakinra leads to improved outcomes in immune effector cell-associated neurotoxicity syndrome.
Among the 15 patients treated, significant reductions in clinical symptoms were observed from baseline to treatment.
The analysis integrates clinical data from multiple treatment centers, emphasizing real-world effectiveness of the intervention.
Further validation in larger trials is necessary to confirm these findings in diverse patient populations.
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Shah et al. (Sun,) studied this question.
synapsesocial.com/papers/69a76046c6e9836116a2cd83
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.226
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