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Safety and Efficacy of Port for CART Administration in Large B-cell Lymphoma | Synapse
March 3, 2026
Safety and Efficacy of Port for CART Administration in Large B-cell Lymphoma
ZH
Zachary Hunzeker
The University of Texas MD Anderson Cancer Center
AL
Anath C. Lionel
The University of Texas MD Anderson Cancer Center
XS
Xiaowen Sun
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Key Points
CAR-T therapy demonstrates safety and efficacy when administered through a port catheter in B-cell lymphoma patients.
Patients reported fewer complications, with a notable decrease in infection rates to 5.2%.
Observational analysis of treatment methods highlights the importance of safe administration routes for CAR-T therapy.
These findings suggest that using a port may enable smoother delivery of CAR-T therapy in an oncology setting.
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Hunzeker et al. (Sun,) studied this question.
synapsesocial.com/papers/69a76066c6e9836116a2d1d3
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.257
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