Polyphthalocyanine-based nanostructure for sono-immunotherapy by reprogramming the tumor microenvironment and blocking immune checkpoint

Key Points

• Reprogramming the tumor microenvironment enhances immune response to therapy—overall improving treatment efficacy.
• Metrics indicated a significant reduction in immune checkpoints, contributing to better cancer cell recognition and targeting.
• Assessment using polyphthalocyanine-based nanostructures in combination with sono-immunotherapy showed promising results.
• Potential impact may enable novel treatments, although further studies in clinical settings are needed.