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March 3, 2026
An unprecedented potent inhibitor of MV4-11 cells: investigations into the mechanism of action beyond FLT3 inhibition
XW
Xiuqi Wang
RD
Rosa Anna DeFilippis
University of California, San Francisco
HG
Huimin Geng
University of California, San Francisco
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Key Points
The potent inhibitor shows significant effects in mv4-11 cells, supporting its potential clinical application.
Researchers observed that treatment resulted in a marked reduction of cell viability by 80% over 48 hours.
Detailed investigations explored mechanisms beyond flt3 signaling, aiming to unravel its broader impact.
This analysis may highlight new therapeutic strategies for targeting mv4-11 cells, but additional studies are essential.
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An unprecedented potent inhibitor of MV4-11 cells: investigations into the mechanism of action beyond FLT3 inhibition | Synapse
Cite This Study
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Wang et al. (Tue,) studied this question.
synapsesocial.com/papers/69a760dfc6e9836116a2e091
https://doi.org/https://doi.org/10.1016/j.bioorg.2026.109601