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March 3, 2026
GLP-1 Receptor Agonist Initiation and Risk of Colorectal Cancer and Colonic Polyps
AM
Anwar Alshaakh Mohd Mari
University of Central Florida
FA
Faris Alamin
ML
Minh Anh Le
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Key Points
Colorectal cancer risk may increase with GLP-1 receptor agonist initiation, highlighting a need for monitoring.
A 15% increase in risk for colorectal cancer was observed within the first two years of treatment.
Analysis of recent health records from 40,000 individuals revealed these concerning trends.
Implications suggest healthcare providers should carefully evaluate GLP-1 receptor agonist use due to potential risks.
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Cite This Study
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Mari et al. (Sun,) studied this question.
synapsesocial.com/papers/69a7614ac6e9836116a2f148
https://doi.org/https://doi.org/10.1016/j.amjms.2026.02.002
GLP-1 Receptor Agonist Initiation and Risk of Colorectal Cancer and Colonic Polyps | Synapse