Uncomplicated Choledocholithiasis in Elderly Patients: A Target Trial Emulation Comparing Observation and ERCP (CHOIcE)

Key Points

• Observation results in significant management outcomes for elderly patients with choledocholithiasis, allowing for less invasive interventions.
• Key evidence shows that among patients aged 65 and older, adherence to observation protocols can reduce the need for immediate ERCP procedures.
• Target trial emulation methodology was applied to assess clinical outcomes in elderly patients presenting with choledocholithiasis.
• Findings highlight the importance of personalized treatment approaches; further research is needed to confirm long-term benefits.