Taurine Mitigates Microplastic-Induced Neurotoxicity Through Modulation of Neurobehavior, Neurotransmitters, Oxidative Stress, and AKT-1/CREB-1/BDNF Signaling in Mice | Synapse
March 3, 2026
Taurine Mitigates Microplastic-Induced Neurotoxicity Through Modulation of Neurobehavior, Neurotransmitters, Oxidative Stress, and AKT-1/CREB-1/BDNF Signaling in Mice
Key Points
Taurine significantly reduces microplastic-induced neurotoxicity, improving neurobehavior and neurotransmitter levels.
In treated mice, oxidative stress markers decreased by 45%, indicating a protective effect from taurine.
The analysis employs a mouse model to evaluate the interaction between taurine and the AKT-1/CREB-1/BDNF signaling pathways.
Findings support the potential use of taurine as a neuroprotective agent, highlighting the need for further research in human models.