Retraction for Lkb1 deletion in periosteal mesenchymal progenitors induces osteogenic tumors through mTORC1 activation

Key Points

• Osteogenic tumors develop due to Lkb1 deletion, activating mTORC1 signaling.
• Findings revealed a significant 50% incidence of tumors in the studied models.
• Analysis involved the deletion of Lkb1 in periosteal mesenchymal progenitor cells.
• Retraction highlights the need for caution in interpreting Lkb1's role in tumorigenesis.