The moonlighting functions of glycolytic enzymes in tumorigenesis

Key Points

• Glycolytic enzymes play essential roles beyond energy production in cancer cells, impacting their growth dynamics.
• Key findings indicate that these enzymes can act as oncogenes, driving tumorigenesis through metabolic reprogramming.
• Analysis of experimental models demonstrates how glycolytic pathways promote cancer cell survival and proliferation.
• The discovery highlights the potential for targeting metabolic pathways in cancer treatment strategies.