Chronic Administration of Atomoxetine and Methylphenidate Induces Differential Alterations in the Hippocampus and Striatum of Young Rats

Key Points

• Chronic administration of atomoxetine and methylphenidate alters neurotransmission in young rats' brains.
• The hippocampus and striatum show different changes in response to these two drugs after chronic exposure.
• Observational analysis across young rats reveals significant modifications in brain region functionality.
• Findings underscore the need for careful consideration of medication effects during brain development.