Large-bore mechanical thrombectomy vs standard of care for acute high-risk pulmonary embolism: Rationale and design of the PERSEVERE randomized controlled trial

Key Points

• Mechanical thrombectomy shows promise in treating acute high-risk pulmonary embolism, indicating potentially better outcomes.
• The trial specifically targets acute high-risk pulmonary embolism, with emphasis on comparing intervention effectiveness.
• Assessment involves a randomized controlled trial design to measure intervention impacts more precisely and effectively.
• Results may influence clinical guidelines, enhancing treatment strategies for acute pulmonary embolism management.