Coptisine alleviates insulin resistance by suppressing SMARCE1-mediated glycolysis

Key Points

• Coptisine alleviates insulin resistance by effectively suppressing the metabolic pathway of glycolysis.
• The analysis shows a significant reduction in glycolysis activity linked to SMARCE1 impairment.
• Observational analysis of metabolic pathways indicates a potential therapeutic role for coptisine in metabolic disorders.
• The findings may enable new approaches to managing insulin resistance in diverse populations.