Phosphorylation of the α subunit inhibits proteasome assembly and regulates cell cycle in an archaeon

Key Points

• Proteasome assembly is inhibited by phosphorylation of the α subunit, affecting the cell cycle.
• The study reveals that phosphorylation plays a key regulatory role by impacting proteasome function.
• Analysis shows the mechanism of phosphorylation’s effect on archaeal cell cycle control across various conditions.
• Findings may enable future research on cell cycle regulation in other organisms, though specific mechanisms in archaea are spotlighted.