Predictive factors of global cognitive impairment in de novo Parkinson disease with normal cognition at baseline: a 10-year cohort study

Key Points

• Global cognitive impairment shows a significant correlation with specific predictive factors over a decade.
• Key evidence reveals that 35% of patients developed cognitive impairment by the 10-year mark.
• Cohort study assessed patient cognition at baseline and during follow-ups, revealing long-term trends.
• Early identification of predictive factors may lead to tailored interventions for at-risk individuals.