March 3, 2026Open Access

Pre and post introduction of pneumococcal conjugate vaccines in children in Eastern Mediterranean Region and effect on antimicrobial resistance, a narrative review

Key Points

Pneumococcal conjugate vaccines are essential for reducing antimicrobial resistance and disease burden.
Suboptimal vaccine coverage and the emergence of non-vaccine types persist, highlighting significant challenges.
Comprehensive strategies must include improved vaccine coverage, robust surveillance, and targeted public health interventions.
Strengthened antibiotic stewardship is crucial for mitigating the burden of antimicrobial resistance in the region.

Abstract

PCVs play a pivotal role in mitigating AMR and reducing pneumococcal disease burden in the EMR. However, suboptimal vaccine coverage, NVT emergence, and persistent AMR highlight the need for comprehensive strategies, including enhanced coverage of higher valency vaccines, robust surveillance, targeted public health interventions, strengthened antibiotic stewardship, and improved regional collaboration. Addressing these issues can significantly reduce the AMR burden and improve health outcomes across the region.

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Cite This Study

Saleh et al. (Fri,) studied this question.

synapsesocial.com/papers/69a767d9badf0bb9e87e2985 https://doi.org/https://doi.org/10.3389/fmicb.2026.1735082

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