Leonurine alleviates HFD-induced inflammation and dyslipidemia via modulating gut microbiota-derived indole-3-propionic acid signaling

Key Points

• Leonurine significantly reduces inflammation and dyslipidemia, supporting metabolic health.
• The gut microbiota-derived indole-3-propionic acid plays a key role in these beneficial effects.
• Analysis of high-fat diet effects reveals that leonorine impacts gut signaling pathways.
• This highlights the potential for dietary interventions to influence metabolic disorders and support health.