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Cathepsin H as a causal risk factor and therapeutic target in proliferative diabetic retinopathy | Synapse
March 3, 2026
Open Access
Cathepsin H as a causal risk factor and therapeutic target in proliferative diabetic retinopathy
QZ
Qihang Zhou
FY
Fan Yang
SG
Shuxia Guo
Shihezi University
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Key Points
Proliferative diabetic retinopathy is linked to elevated cathepsin H levels, indicating its role as a risk factor.
The study shows a significant association with a p-value less than 0.05, emphasizing the importance of cathepsin H.
Assessment using clinical and molecular data reveals cathepsin H as a potential therapeutic target for treatment.
This finding supports the need for further investigation into cathepsin H’s role in diabetic complications.
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Zhou et al. (Fri,) studied this question.
synapsesocial.com/papers/69a768b0badf0bb9e87e59e6
https://doi.org/https://doi.org/10.1186/s12967-025-07314-4