Crystallographic and computational investigation of a bent-core Schiff base Ni( ii ) complex with DNA and protein binding studies

Key Points

• To design and synthesize a bent-core Schiff base ligand and its Ni II complex, and examine their interactions with DNA and proteins.
• Synthesis of the Schiff base ligand (HL) and its Ni II complex [Ni(L)2] (1)
• Crystallographic analysis of the complex
• Binding studies with DNA and proteins
• Characterization of the bent-core Schiff base ligand and Ni II complex
• Evidence of DNA and protein binding interactions
• Potential implications in biochemical applications observed.